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Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
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Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy

El. knyga: 207,39 €

This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section cover…
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  • Leidėjas:
  • Metai: 20160830
  • ISBN-10: 3319422235
  • ISBN-13: 9783319422237
  • Kalba: Anglų

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This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.

The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
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207,39 €El. knyga

  • Leidėjas: Springer-Verlag GmbH
  • Metai: 20160830
  • ISBN-10: 3319422235
  • ISBN-13: 9783319422237
  • Kalba: Anglų

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