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Aprašymas
This detailed volume explores approaches used for identifying new protein therapeutics followed by methods designed to define the therapeutic functions and molecular targets. Cell and preclinical animal models of disease are then assessed for responses to newer protein reagents, including methods from molecular and cellular assays, animal models, and AI analysis of protein interactions. Finally, clinical trials allow for final testing of protein therapeutic safety and efficacy, allowing a final assessment of potential treatment efficacy for protein therapeutics, so the book concludes with a chapter on establishing a clinical trials site. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Protein Therapeutics serves as an ideal guide for researchers looking to develop new classes of drugs for treating disease, whether for rare or common disorders.
This detailed volume explores approaches used for identifying new protein therapeutics followed by methods designed to define the therapeutic functions and molecular targets. Cell and preclinical animal models of disease are then assessed for responses to newer protein reagents, including methods from molecular and cellular assays, animal models, and AI analysis of protein interactions. Finally, clinical trials allow for final testing of protein therapeutic safety and efficacy, allowing a final assessment of potential treatment efficacy for protein therapeutics, so the book concludes with a chapter on establishing a clinical trials site. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls.
Authoritative and practical, Protein Therapeutics serves as an ideal guide for researchers looking to develop new classes of drugs for treating disease, whether for rare or common disorders.
Atsiliepimai