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This book explores the science, design, and application of biomaterials in modern healthcare, presenting clear explanations of fundamental principles, material properties, and biocompatibility alongside detailed discussions of degradation, stability, and surface¿modification strategies; it highlights practical uses in tissue engineering, wound healing, drug¿delivery systems, biosensors, and clinical specialties such as orthopedics, cardiovascular medicine, dentistry, ophthalmology, and neural therapies, while also examining emerging innovations including nanomaterials and additive manufacturing, addressing regulatory and ethical considerations, and integrating case studies, recent advances, and critical analyses of current challenges to equip students, researchers, and professionals with the knowledge needed to understand and contribute to the evolving role of biomaterials in biomedical engineering.