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Giving much more attention to noninferiority testing, this second edition provides readers with a rich repertoire of efficient solutions to specific equivalence and noninferiority testing problems frequently encountered in the analysis of real data sets. It also includes new chapters on equivalence tests for multivariate data and tests for relevant differences between treatments. Drawing from real-life medical research, the author uses numerous examples throughout to illustrate the methods. Updated computer programs in SAS, Fortran, and R for facilitating the routine application of testing procedures are available online at www.crcpress.com