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A new attempt to acknowledge and rekindle interest in the experimental foundation of behavioral medicine, this volume focuses on the relevance of conditioning processes in the development of clinically relevant intervention strategies. It provides illustrations of the basic conditioning effects in the regulation of physiological responses, the role of conditioning in selected disease models, the precise application of conditioning principles, and speculative analyses of the potential of conditioning in the modification of clinically relevant responses. Issues involved in teaching both the fundamentals and the applied components of behavioral medicine are addressed.