Design and Analysis of Bioavailability and Bioequivalence Studies (el. knyga) (skaityta knyga) | knygos.lt

Aprašymas

This practical reference/text, written at a basic mathematical and statistical level, presents important statistical concepts for assessing bioequivalence through real examples and provides a thorough, unified discussion of the design and analysis of bioavailability and bioequivalence studies. bioavailability methods, Design and Analysis of Bioavailability and Bioequivalence Studies: supplies a simple formula for sample size determination; explains techniques for checking model assumptions and detecting outlying data; compares the additive model and the multiplicative model; demonstrates statistical methods of assessing more than two formulations; and delineates bioequivalence assessment with negligible plasma levels. Analysis of Bioavailability and Bioequivalence Studies: contains various study designs based on different needs and objectives; offers over 400 display equations but requires no mathematics beyond simple algebra; and incorporates time-saving SAS programmes and an appendix of statistical tables. intended for biostatisticians; applied statisticians; biometricians; pharmacologists; clinical, industrial and research pharmacists; and drug regulatory personnel; as well as an for all upper-level undergraduate and graduate courses in bioavailability and bioequivalence, pharmacokinetics, pharmaceutics and biostatistics.