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We live in an era of depression, a condition that causes extensive suffering for individuals and families and saps our collective productivity. Yet there remains considerable confusion about how to understand depression. Depression: Integrating Science, Culture, and Humanities looks at the varied and multiple models through which depression is understood. Highlighting how depression is increasingly seen through models of biomedicine and through biomedical catch-alls such as "broken brains" and "chemical imbalances" psychiatrist and cultural studies scholar Bradley Lewis shows how depression is also understood through a variety of other contemporary models. Furthermore, Lewis explores the different ways that depression has been categorized, described, and experienced across history and across cultures.