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Beta-Arrestins
Beta-Arrestins

Kaina internetu: 200,09 €

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This volume looks at various approaches to study the pleiotropic roles of b-arrestins (b-arrs) in the control of signal transduction, and the resulting cellular and in vivo consequences that arise. The chapters in this book cover diverse topics around b-arrs such as their established roles in GPCR regulation and trafficking; regulatory scaffolding functions of b-arrs in MAPK signaling, cAMP hydrolysis and cytoskeletal dynamics; proteomic analysis of the b-arr interactome; mathematical modellin…
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  • Leidėjas:
  • Metai: 20190424
  • ISBN-10: 1493991574
  • ISBN-13: 9781493991570
  • Formatas: 18.1 x 26.1 x 3.2 cm, kieti viršeliai
  • Kalba: Anglų

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This volume looks at various approaches to study the pleiotropic roles of b-arrestins (b-arrs) in the control of signal transduction, and the resulting cellular and in vivo consequences that arise. The chapters in this book cover diverse topics around b-arrs such as their established roles in GPCR regulation and trafficking; regulatory scaffolding functions of b-arrs in MAPK signaling, cAMP hydrolysis and cytoskeletal dynamics; proteomic analysis of the b-arr interactome; mathematical modelling of b-arr signaling networks; functional selectivity involving biased ligands; nucleocytoplasmic trafficking and primary cilia-associated functions of b-arrs; conformational plasticity of b-arrs; and the roles of b-arrs in allergic inflammation, Type 2 Diabetes, Parkinson's disease, and cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and authoritative, Beta-Arrestins: Methods and Protocols is a valuable resource for researchers interested in learning more about the function and regulation of b-arrestins.

  • Kaina internetu: 200,09 €
  • Už šią prekę gausite 2 knygų eurų!
  • Išsiųsime per 16–20 d.d.

Formatai:

200,09 € Nauja knyga
kieti viršeliai

  • Leidėjas: Springer-Verlag GmbH
  • Metai: 20190424
  • ISBN-10: 1493991574
  • ISBN-13: 9781493991570
  • Formatas: 18.1 x 26.1 x 3.2 cm, kieti viršeliai
  • Kalba: Anglų

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